An aortic occlusion and perfusion device includes an expandable member configured to expand within the aorta. A catheter extends proximally from the expandable member in fluid communication with the expandable member. The catheter defines openings through which blood can pass with one or more of the openings located proximal to the expandable member and one or more of the openings located within the expandable member. The catheter defines a lumen in fluid communication with the one or more openings located within the expandable member, the lumen terminating at a terminus such that the lumen is not in fluid communication with a distal end portion of the catheter. A flow control sheath is disposed around the catheter proximal to the expandable member such that axial movement of the flow control sheath relative to the catheter selectively occludes or uncovers the one or more openings located proximal to the expandable member.