- 专利标题： NEISSERIA MENINGITIDIS COMPOSITIONS AND METHODS THEREOF
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申请号： US17764153申请日： 2020-09-24
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公开(公告)号： US20220401544A1公开(公告)日： 2022-12-22
- 发明人: Annaliesa Sybil Anderson , John Lance Perez , Kathrin Ute Jansen , Paul Liberator , Cuiwen Tan , Thomas Richard Jones , Johannes Frederik Beeslaar , Judith Absalon , Jason Douglas Maguire , Shannon Lea Harris
- 申请人： Pfizer Inc.
- 申请人地址： US NY New York
- 专利权人： Pfizer Inc.
- 当前专利权人： Pfizer Inc.
- 当前专利权人地址： US NY New York
- 国际申请： PCT/IB2020/058928 WO 20200924
- 主分类号： A61K39/095
- IPC分类号： A61K39/095 ; A61P31/04 ; A61K47/02
摘要：
NEW MATERIAL: Recombinant plasmid pTPGIF2 having a size of 4,660 base pairs and a structure obtained by inserting a DNA having a size of 52 base pairs and containing a sequence coding somatostatin into a BamHI incision site of a plasmid vector pTP70-1 capable or fusing a heteropeptide to a carboxy-terminal of a dihydrofolic acid reductase gene of E. coli. USE: Producton of fused protein containing somatostatin.
PREPARATION: A somatostatin gene is integrated into a plasmid vector pTP70-1. pTPGIF2 is kept in stable state when introduced into E. coli. C600 strain. The E. coli. C600 train containing pTPGIF2 is deposited in Fermentation Research institute as FERM BP-1577.
PREPARATION: A somatostatin gene is integrated into a plasmid vector pTP70-1. pTPGIF2 is kept in stable state when introduced into E. coli. C600 strain. The E. coli. C600 train containing pTPGIF2 is deposited in Fermentation Research institute as FERM BP-1577.
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