Systems and methods facilitate wellbore planning and cleaning operations, and generally relate to use of a planning system that interfaces with a simulator. The planner and simulator interact, via the interface, to evaluate various wellbore plans and the effects of the plans on cuttings accumulation, cuttings transport, wellbore geometry, or other borehole conditions. The cost, risk, time, or other associated outcomes of the plans can be compared and evaluated and selected. The plan is then implemented. Planning can continue in substantially real-time to continue modifying the plan to provide a desired balance of outcomes.