- 专利标题： T-CELL COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
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申请号： US17763548申请日： 2020-09-24
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公开(公告)号： US20220409716A1公开(公告)日： 2022-12-29
- 发明人: Michael Keller , Catherine Mary Bollard , Ryo Hanajiri , Gelina Sani , Lisbeth Kim Green , Jeff Cohen , Stanislav V. Sosnovtsev
- 申请人： Children's National Medical Center , The United States of America, as represented by the Secretary, Dept. of Health and Human Service
- 申请人地址： US DC Washington; US MD Bethesda
- 专利权人： Children's National Medical Center,The United States of America, as represented by the Secretary, Dept. of Health and Human Service
- 当前专利权人： Children's National Medical Center,The United States of America, as represented by the Secretary, Dept. of Health and Human Service
- 当前专利权人地址： US DC Washington; US MD Bethesda
- 国际申请： PCT/US20/52559 WO 20200924
- 主分类号： A61K39/12
- IPC分类号： A61K39/12 ; A61P31/14
摘要：
The present disclosure provides adoptive T-cell compositions, therapies, and processes of manufacture that are tailored for treatment or prevention of a subject with a norovirus infection, and, in some embodiments, for those subjects who are candidates for hematopoietic stem cell treatments, subjects who have undergone hematopoietic stem cell treatments, and subjects that have, are diagnosed with or suspected of having primary immunodeficiency disorders.
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