- 专利标题: CHROMOGENIC PEROXIDASE SUBSTRATES
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申请号: US17885188申请日: 2022-08-10
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公开(公告)号: US20230002816A1公开(公告)日: 2023-01-05
- 发明人: Jesper Lohse , Mike Paw Maischnack Hansen
- 申请人: Agilent Technologies, Inc.
- 申请人地址: US CA Santa Clara
- 专利权人: Agilent Technologies, Inc.
- 当前专利权人: Agilent Technologies, Inc.
- 当前专利权人地址: US CA Santa Clara
- 主分类号: C12Q1/6841
- IPC分类号: C12Q1/6841 ; G01N33/58 ; C07D311/82 ; C07D311/90 ; C07D493/10 ; C12N9/08 ; C12N9/96 ; C12Q1/28
摘要:
Chromogenic conjugates for color-based detection of targets are described. The conjugates comprise a chromogenic moiety such as a rhodamine, rhodol or fluorescein. The chromogenic moiety is linked to a peroxidase substrate. The chromogenic conjugates can be used in immunohistochemical analysis and in situ hybridization. The conjugates can be used to detect 1, 2, 3 or more targets in a sample by color.