A patient support apparatus and a removable battery usable with the patient support apparatus. The patient support apparatus may include a support frame with a patient support deck disposed on the support frame and a lift assembly having a powered lift actuator to adjust the support frame. The patient support apparatus may further include a battery retention system coupled to the support frame. The battery retention system may include a mount base and a battery receiver pivotably coupled to the mount base for movement between a locked state and an unlocked state for permitting removal of the battery from the battery retention system.