An introducer sheath for use in delivering devices includes a proximal portion opposite a distal portion and a body portion extending between the proximal portion and the distal portion, the body portion defining a lumen of the introducer sheath configured for receiving at least one device, at least one bypass opening positioned in the proximal portion of the introducer sheath such that the bypass opening extends from an exterior of the introducer sheath to the lumen of the introducer sheath, and at least one plug configured to positioned within the lumen of the introducer sheath and to inhibit the flow of blood into the lumen proximal of the plug.