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公开(公告)号:US20250064728A1
公开(公告)日:2025-02-27
申请号:US18805710
申请日:2024-08-15
Applicant: Boston Scientific Scimed, Inc.
Inventor: Nicolas Ball-Jones , Joseph Thomas Delaney, JR. , Yen-Hao Hsu , Cristian Parisi
Abstract: In some aspects, the present disclosure provides a system for forming a hydrogel composition that comprises (a) a first reservoir containing a reactive polymer that comprises a plurality of first reactive groups; (b) a second reservoir containing a multifunctional compound that comprises a plurality of second reactive groups, the second reactive groups reacting with the first reactive groups to form covalent bonds at a pH greater than 7.4; and (c) a third reservoir containing a biologically innocuous buffer having a pH in a range of 8 to 12. Other aspects of the present disclosure pertain methods of treatment using such systems.
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公开(公告)号:US12233261B2
公开(公告)日:2025-02-25
申请号:US17459592
申请日:2021-08-27
Applicant: Boston Scientific Scimed, Inc.
Inventor: Sarah M. Gruba , James A. Klos , James P. Rohl , Sandra L. Weeda , Troy A. Giese
Abstract: A medical system includes a shaft having a proximal end and a distal end, a balloon attached to the distal end of the shaft, the balloon movable between an expanded state and a deflated state where a maximum diameter of the balloon is greater in the expanded state than in the deflated state, and an electrode is attached to the shaft where a portion of the balloon includes a plurality of apertures fluidly connecting an interior of the balloon to an exterior of the balloon.
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公开(公告)号:US12232911B2
公开(公告)日:2025-02-25
申请号:US17447163
申请日:2021-09-08
Applicant: Boston Scientific Scimed, Inc.
Inventor: Gary Kappel , Barry Weitzner , Paul Smith , Erin Daly
Abstract: A support mechanism for a medical device may include an adjustable support that includes a plurality of elongate members movable relative to one another. The support mechanism may also include a bracket coupled to the adjustable support. The bracket may be adapted to be coupled to a first medical device that extends along a longitudinal axis. The support mechanism may also include an instrument holder that extends along a central axis. The instrument holder may be movably coupled to the bracket and adapted to be coupled to a second medical device. The bracket and the instrument holder may be oriented such that central axis of the instrument holder intersects the longitudinal axis at an angle.
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公开(公告)号:US12232805B2
公开(公告)日:2025-02-25
申请号:US17499062
申请日:2021-10-12
Applicant: Boston Scientific Scimed, Inc.
Inventor: Hyun Wook Kang , Raymond Adam Nemeyer , Michael Ray Hodel
Abstract: A laser resonator includes a gain medium that produces light from pump energy and a variable light attenuator, which receives light and emits either (i) a first light including a continuous series of micropulses, or (ii) a second light including a series of macropulses at spaced time intervals, where each macropulse includes a series of micropulses. Each micropulse has a duration of 0.1 to 10 microseconds, and a duration of each macropulse is less than the time interval between each macropulse, and the micropulses have a frequency of 5 kHz to 40 kHz.
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公开(公告)号:US12232697B2
公开(公告)日:2025-02-25
申请号:US17806624
申请日:2022-06-13
Inventor: Arun Adhikarath Balan , Rajivkumar Singh , Deepak Kumar Sharma , Paul Smith
IPC: A61B1/00 , A61B1/005 , A61B17/122 , A61B17/128 , A61B17/00
Abstract: A clipping system includes a cap configured to be mounted over a distal end of an endoscope. A clip mountable over the cap to move between an insertion configuration, in which first and second jaws extend over opposing portions of the cap so that the first and second jaws are separated from one another, a review configuration, in which the clip is moved distally relative to the cap so that a portion of the clip extends distally until at least a portion of the clip extends into a field of view of the optical system of an endoscope on which the cap is mounted, and a deployed configuration in which the clip is moved distally off of the clip so that the first and second jaws are drawn toward one another under the bias of the at least one hinge to close over tissue received therebetween.
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公开(公告)号:US20250059237A1
公开(公告)日:2025-02-20
申请号:US18804679
申请日:2024-08-14
Applicant: Boston Scientific Scimed, Inc.
Inventor: Joseph Thomas Delaney, JR. , Rick Dorn , Yen-Hao Hsu , Cristian Parisi
Abstract: In various aspects, the present disclosure pertains to methods of forming an iodinated peptide compound that comprises: (a) forming a multifunctional precursor compound comprising (i) a residue of an amine-protected peptide that comprises two or more amino acid residues with primary-amine-containing side groups and (ii) a multifunctional moiety linked to the amine-protected peptide residue through an amide group or an ester group; (b) reacting the multifunctional precursor compound in an amide coupling reaction or an esterification coupling reaction with an iodinated compound to form an iodinated, amine-protected peptide compound comprising n iodinated moieties that are covalently attached to the amine-protected peptide residue through a residue of the multifunctional moiety; and (c) deprotecting the iodinated, amine-protected peptide compound to form the iodinated peptide compound.
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公开(公告)号:US20250057407A1
公开(公告)日:2025-02-20
申请号:US18938545
申请日:2024-11-06
Applicant: Boston Scientific Scimed, Inc.
Inventor: Christopher L. OSKIN
Abstract: A medical device may include an insertion portion longitudinally extending between a proximal end and a distal end. The insertion portion may define a channel extending therethrough. The medical device may further include a handle coupled to the proximal end of the insertion portion. The handle may further include an irrigation port in fluid communication with the channel and coupled to a source of irrigation fluid. Additionally, the handle may include an actuator and a pressurizer. Manipulation of the actuator may be configured to actuate the pressurizer to urge irrigation fluid distally through the channel.
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公开(公告)号:US12226793B2
公开(公告)日:2025-02-18
申请号:US18496982
申请日:2023-10-30
Applicant: Boston Scientific Scimed, Inc.
Inventor: Andrew Pic , Joseph King , Amanda Smith , Jessica Grimsby , John Favreau , Lauren Lydecker
Abstract: A device for fluidizing and delivering a powdered agent, including a canister extending longitudinally from a first to a second end and defining a space within which a powdered agent is received, an inlet coupleable to a gas source for supplying gas to the space to fluidize the powdered agent to create a fluidized mixture, an outlet via which the gas mixture is delivered to a target area, a tube extending from the outlet into the interior space, the tube including a slot extending through a wall thereof so that gas mixture is passable from the interior space through the outlet via the second end and the slot, and a door movably coupled to the tube so that the door is movable over the slot to control a size of the slot open to the interior space of the canister.
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公开(公告)号:US20250049556A1
公开(公告)日:2025-02-13
申请号:US18928829
申请日:2024-10-28
Applicant: Boston Scientific Scimed, Inc.
Inventor: Kenneth F. Binmoeller , Sieu T. Duong , Hanh Huu Duong , Thao Vi Nguyen
Abstract: A tissue lumen stent is provided with a body having an elongated tubular configuration and a foreshortened configuration. In the foreshortened configuration, downstream and upstream ends of the body expand radially into downstream and upstream flange structures, leaving a generally cylindrical saddle region therebetween. In some embodiments, the flange structures are non-symmetrical with respect to one another. Systems and methods of using the stents are also disclosed.
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公开(公告)号:US20250049420A1
公开(公告)日:2025-02-13
申请号:US18796486
申请日:2024-08-07
Applicant: Boston Scientific Scimed, Inc.
Inventor: Paul SMITH , Scott E. BRECHBIEL , Andrew James SCHAUBHUT , Narunn SUON , Tony SOUKALOPOULOS , Naomi GANNON
IPC: A61B10/02
Abstract: A cytology brush including a base wire having a distal end; at least one coiled loop; and a plurality of bristles. The coiled loop is configured to at least partially surround a portion of a guide wire such that the cytology brush is longitudinally movable along and adjacent to the guide wire.
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