The embodiments of the present application relate to the technical field of wireless communication, and provide a signal transmission method and device, which are used to more flexibly indicate the transmission of information when PUSCH uplink transmission is performed. The method comprises: a network side device first determines transmission information that is used for uplink signal transmission and that corresponds to first resource information, then generates transmission indication information according to the transmission information, and finally indicates the transmission indication information to a terminal so that the terminal determines, according to the transmission indication information, transmission information corresponding to an uplink signal on a frequency domain resource, and transmits the uplink signal according to the transmission information. Since there is a correspondence between the transmission information and the first resource information, the transmission information can be determined according to the first resource information, thus the transmission information can be indicated more flexibly.