- 专利标题： DHODH INHIBITOR FOR THE TREATMENT OF COVID-19
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申请号： US17923825申请日： 2021-05-07
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公开(公告)号： US20230172915A1公开(公告)日： 2023-06-08
- 发明人: Nikolai A. NARYSHKIN , Jason GRACI , John BAIRD , Joseph COLACINO , Marla L. WEETALL , Liangxian CAO
- 申请人： PTC THERAPEUTICS, INC.
- 申请人地址： US NJ South Plainfield
- 专利权人： PTC THERAPEUTICS, INC.
- 当前专利权人： PTC THERAPEUTICS, INC.
- 当前专利权人地址： US NJ South Plainfield
- 国际申请： PCT/US2021/031326 2021.05.07
- 进入国家日期： 2022-11-07
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; A61K31/675 ; A61P31/14
摘要：
One aspect described herein includes a method for treating coronavirus 2019 disease (COVID-19) caused by severe respiratory syndrome coronavirus 2 (SARS-CoV-2) by administering an effective amount of a DHODH inhibitor. Another aspect described herein includes a method of treating COVD-19 by administering 4-chlorophenyl (S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indole-2-carboxylate (PTC299), or a pharmaceutically acceptable salt thereof.
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