Invention Publication
- Patent Title: CONDENSED SUBSTITUTED HYDROPYRROLES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4
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Application No.: US17920899Application Date: 2021-04-23
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Publication No.: US20230183218A1Publication Date: 2023-06-15
- Inventor: Craig W. Lindsley , P. Jeffrey Conn , Darren W. Engers , Aaron M. Bender , Changho Han
- Applicant: Vanderbilt University
- Applicant Address: US TN Nashville
- Assignee: Vanderbilt University
- Current Assignee: Vanderbilt University
- Current Assignee Address: US TN Nashville
- International Application: PCT/US2021/028763 2021.04.23
- Date entered country: 2022-10-24
- Main IPC: C07D405/14
- IPC: C07D405/14 ; C07D403/12 ; C07D409/14 ; C07D417/14 ; C07D471/04 ; C07D403/14 ; C07D401/14 ; C07D487/04
Abstract:
Disclosed herein are substituted hexahydro-1H-cyclopenta[c]pyrrole compounds, which may be useful as antagonists of the muscarinic acetylcholine receptor M4 (mAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating disorders using the compounds and compositions.
Information query
