Invention Publication
- Patent Title: TECHNIQUE FOR CONTROLLING QUALITY OF HUMAN PLURIPOTENT STEM CELLS USING CULTURE SUPERNATANT
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Application No.: US18009632Application Date: 2021-06-11
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Publication No.: US20230204600A1Publication Date: 2023-06-29
- Inventor: Tomoko WATANABE , Hiroaki TATENO , Shuuji MAWARIBUCHI , Yoshikazu HARAMOTO
- Applicant: National Institute of Advanced Industrial Science and Technology
- Applicant Address: JP Chiyoda-ku, Tokyo
- Assignee: National Institute of Advanced Industrial Science and Technology
- Current Assignee: National Institute of Advanced Industrial Science and Technology
- Current Assignee Address: JP Chiyoda-ku, Tokyo
- Priority: JP 20102063 2020.06.12
- International Application: PCT/JP2021/023128 2021.06.11
- Date entered country: 2022-12-09
- Main IPC: G01N33/68
- IPC: G01N33/68

Abstract:
An object of the present invention is to provide a novel method that enables determination or evaluation of the undifferentiated state of human pluripotent stem cells simply, efficiently and non-invasively. The present invention provides a method for determining or evaluating the undifferentiated state of human pluripotent stem cells, comprising a step of detecting or measuring fibronectin in a culture supernatant of human pluripotent stem cells.
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