- 专利标题： 2,4,6-TRI-SUBSTITUTED PYRIMIDINE COMPOUNDS AS ATR KINASE INHIBITORS
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申请号： US17926533申请日： 2021-05-20
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公开(公告)号： US20230212160A1公开(公告)日： 2023-07-06
- 发明人: Yanping Zhao , Bin Liu , Yuanyuan Jiang , Weiting Zhong , Huifen Xu , Hongjun Wang , Li Mao , Jingtao Li , Honglei Zhang , Chuangchuang Huang , Jing .. Li , Jing Zhao , Weina Liu , Nana Tian , Liying Zhou , Yanan Liu
- 申请人： BEIJING TIDE PHARMACEUTICAL CO., LTD.
- 申请人地址： CN Beijing
- 专利权人： BEIJING TIDE PHARMACEUTICAL CO., LTD.
- 当前专利权人： BEIJING TIDE PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： CN Beijing
- 优先权： CN 2010429678.7 2020.05.20 CN 2110418026.8 2021.04.19
- 国际申请： PCT/CN2021/094871 2021.05.20
- 进入国家日期： 2022-11-18
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; C07D471/04 ; C07D405/14 ; A61P35/02 ; A61P15/08 ; A61P35/00
摘要：
Provided are compounds represented by general formula (I), which can be used for treating ATR kinase-mediated diseases, such as proliferative diseases, such as cancer. Further provided are a pharmaceutical composition of the compound represented by general formula (I), a use thereof in treating ATR kinase-mediated diseases, and a preparation thereof.
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