- 专利标题： COMPOSITION FOR DIAGNOSING MUSCULOSKELETAL DISEASES, COMPOSITION FOR PREVENTING OR TREATING MUSCULOSKELETAL DISEASES, AND USE THEREOF
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申请号： US18007182申请日： 2021-07-02
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公开(公告)号： US20230235402A1公开(公告)日： 2023-07-27
- 发明人: Hyun Chul JO , Young-il HWANG , Jin-Hee KIM , Jin-Hong KIM , Jae-Hyung LEE , Hyun-Ju LIM , Ah-Young LEE , Seung Yeon LEE , Ji-Hye YEA , Yeasol KIM
- 申请人： SEOUL NATIONAL UNIVERSITY HOSPITAL , SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , CHEONGJU UNIVERSITY INDUSTRY & ACADEMY COOPERATION FOUNDATION
- 申请人地址： KR Seoul
- 专利权人： SEOUL NATIONAL UNIVERSITY HOSPITAL,SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION,CHEONGJU UNIVERSITY INDUSTRY & ACADEMY COOPERATION FOUNDATION
- 当前专利权人： SEOUL NATIONAL UNIVERSITY HOSPITAL,SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION,CHEONGJU UNIVERSITY INDUSTRY & ACADEMY COOPERATION FOUNDATION
- 当前专利权人地址： KR Seoul; KR Seoul; KR Cheongju-si Chungcheongbuk-do
- 优先权： KR 20200095891 2020.07.31
- 国际申请： PCT/KR2021/008404 2021.07.02
- 进入国家日期： 2023-01-27
- 主分类号： C12Q1/6883
- IPC分类号： C12Q1/6883 ; G01N33/68 ; A61K38/17 ; A61P21/00
摘要：
A composition suitable for diagnosing a musculoskeletal disease and a composition suitable for preventing or treating a musculoskeletal disease are disclosed. The composition contains zinc finger protein with KRAB and SCAN domains 8 (Zkscan8) protein, which can be effectively used as an excellent biomarker for obtaining accurate information about the occurrence and progression stages of a musculoskeletal disease, specifically a tendon disease or a ligament disease. The compositions containing Zkscan8 can be effectively used for preventing or treating a musculoskeletal disease through Zkscan8 overexpression.
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