专利检索 ap:("SEOUL NATIONAL UNIVERSITY HOSPITAL" OR "SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION" OR "CHEONGJU UNIVERSITY INDUSTRY & ACADEMY COOPERATION FOUNDATION") AND inv:"Yeasol KIM" 第 1 页

1.

发明公开
COMPOSITION FOR DIAGNOSING MUSCULOSKELETAL DISEASES, COMPOSITION FOR PREVENTING OR TREATING MUSCULOSKELETAL DISEASES, AND USE THEREOF 审中-公开

公开(公告)号：US20230235402A1

公开(公告)日：2023-07-27

申请号：US18007182

申请日：2021-07-02

申请人： SEOUL NATIONAL UNIVERSITY HOSPITAL , SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , CHEONGJU UNIVERSITY INDUSTRY & ACADEMY COOPERATION FOUNDATION

发明人： Hyun Chul JO , Young-il HWANG , Jin-Hee KIM , Jin-Hong KIM , Jae-Hyung LEE , Hyun-Ju LIM , Ah-Young LEE , Seung Yeon LEE , Ji-Hye YEA , Yeasol KIM

IPC分类号： C12Q1/6883 , G01N33/68 , A61K38/17 , A61P21/00

CPC分类号： C12Q1/6883 , G01N33/6887 , A61K38/17 , A61P21/00 , C12Q2600/158 , G01N2800/10

摘要： A composition suitable for diagnosing a musculoskeletal disease and a composition suitable for preventing or treating a musculoskeletal disease are disclosed. The composition contains zinc finger protein with KRAB and SCAN domains 8 (Zkscan8) protein, which can be effectively used as an excellent biomarker for obtaining accurate information about the occurrence and progression stages of a musculoskeletal disease, specifically a tendon disease or a ligament disease. The compositions containing Zkscan8 can be effectively used for preventing or treating a musculoskeletal disease through Zkscan8 overexpression.