发明公开
- 专利标题： METHODS, SYSTEMS, AND KITS FOR TREATMENT OF INFLAMMATORY DISEASES TARGETING TL1A
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申请号： US18316811申请日： 2023-05-12
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公开(公告)号： US20230272098A1公开(公告)日： 2023-08-31
- 发明人: Laurens KRUIDENIER , Mahyar SABRIPOUR , Jeffry D. Watkins , Cindy T. DICKERSON , Rafael ROJAS , Matthew REISSMAN , Patricia MCNEELEY , Janine BILSBOROUGH , Dermot P. MCGOVERN , Dalin LI
- 申请人： PROMETHEUS BIOSCIENCES, INC. , CEDARS-SINAI MEDICAL CENTER
- 申请人地址： US CA San Diego
- 专利权人： PROMETHEUS BIOSCIENCES, INC.,CEDARS-SINAI MEDICAL CENTER
- 当前专利权人： PROMETHEUS BIOSCIENCES, INC.,CEDARS-SINAI MEDICAL CENTER
- 当前专利权人地址： US CA San Diego
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C12Q1/6883 ; C12Q1/6851 ; A61P1/04
摘要：
Provided are methods, systems, and kits for selecting a subject for treatment with an inhibitor of Tumor necrosis factor-like cytokine 1A (TL1A) activity or expression based on a presence of one or more genotypes associated with a positive therapeutic response to the inhibitor of TL1A. Also provided are methods, systems and kits for detecting the one or more genotypes described herein.
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