- 专利标题: TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE ANTIBODY RESPONSES
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申请号: US18063610申请日: 2022-12-08
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公开(公告)号: US20230321224A1公开(公告)日: 2023-10-12
- 发明人: Christopher Fraser , Takashi Kei Kishimoto , Roberto A. Maldonado
- 申请人: Selecta Biosciences, Inc.
- 申请人地址: US MA Watertown
- 专利权人: Selecta Biosciences, Inc.
- 当前专利权人: Selecta Biosciences, Inc.
- 当前专利权人地址: US MA Watertown
- 分案原申请号: US13457994 2012.04.27
- 主分类号: A61K39/385
- IPC分类号: A61K39/385 ; A61K39/35 ; G01N33/50 ; G01N33/569 ; A61K39/00 ; A61K9/127 ; A61K9/51 ; A61K38/38 ; A61K47/50 ; A61K47/52 ; A61K47/54 ; A61K47/59 ; A61K47/64 ; A61K47/69 ; B82Y5/00 ; A61K39/36 ; A61K31/192 ; A61K9/14 ; A61K38/13 ; A61K38/18
摘要:
Disclosed are synthetic nanocarrier compositions, and related methods, comprising MHC Class II-restricted epitopes and immunosuppressants that provide tolerogenic immune responses, such as a reduction in CD4+ T cell help specific to an antigen.
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