- 专利标题： QUINAZOLINE-2,4-DIAMINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT
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申请号： US18246178申请日： 2021-09-16
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公开(公告)号： US20230365530A1公开(公告)日： 2023-11-16
- 发明人: Jung Jin HWANG , Sang Eun PARK , Dong Eun KIM , Ji-Ye HONG , Choung-Soo KIM , Woo Chan SON , Shinae KIM , Sugyeong KWON , Kyungjin JUNG , Nayeon KIM , Jina KIM , Kyung-Hee KIM , Jung Wook CHIN , Sung Jin CHO , Sehan LEE , Eunju CHA , Jeongmin JOO , Ji Sun HWANG , Jeong-Eun PARK , Ji Hoon YU , Eunmi HONG , Young-Hoon PARK , Ju-Hee LEE
- 申请人： THE ASEAN FOUNDATION , DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION , UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
- 申请人地址： KR Seoul
- 专利权人： THE ASEAN FOUNDATION,DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION,UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
- 当前专利权人： THE ASEAN FOUNDATION,DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION,UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
- 当前专利权人地址： KR Seoul
- 优先权： KR 20200121587 2020.09.21
- 国际申请： PCT/KR2021/012661 2021.09.16
- 进入国家日期： 2023-03-21
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; A61K45/06 ; A61P35/00 ; C07D401/12 ; C07D239/95
摘要：
A compound, a stereoisomer thereof, a hydrate thereof, or a pharmaceutically acceptable salt thereof, provided as one aspect of the present invention, exhibits a high inhibitory ability on euchromatic histone-lysine N-methyltransferase 2 (EHMT2), and thus, the compound can be usefully used for the treatment of cancer.
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