- 专利标题： Rapidly synthesized extracellular matrix-based gels and patterning techniques, from micro- to macro-scale
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申请号： US18317526申请日： 2023-05-15
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公开(公告)号： US20230381373A1公开(公告)日： 2023-11-30
- 发明人: Michael Mak , Xiangyu Gong
- 申请人： Yale University
- 申请人地址： US CT New Haven
- 专利权人： Yale University
- 当前专利权人： Yale University
- 当前专利权人地址： US CT New Haven
- 主分类号： A61L27/24
- IPC分类号： A61L27/24 ; A61L27/26 ; A61L27/50
摘要：
In some aspects, the present invention provides a method of forming crowded collagen based constructs, having the steps of providing a collagen solution in a buffer, providing a macromolecular bath solution, and delivering the collagen solution into the macromolecular bath solution to form crowded collagen constructs. In other aspects, the present invention provides a method of forming crowded cellular based constructs, having the steps of providing a cellular solution in a buffer, providing a macromolecular bath solution, and delivering the cellular solution into the macromolecular bath solution to form crowded cellular constructs.
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