According to some embodiments, a system, method and non-transitory computer-readable medium are provided to protect a cyber-physical system having a plurality of monitoring nodes comprising: a normal space data source storing, for each of the plurality of monitoring nodes, a series of normal monitoring node values over time that represent normal operation of the cyber-physical system; a situational awareness module including an abnormal data generation platform, wherein the abnormal data generation platform is operative to generate abnormal data to represent abnormal operation of the cyber-physical system using values in the normal space data source and a generative model; a memory for storing program instructions; and a situational awareness processor, coupled to the memory, and in communication with the situational awareness module and operative to execute the program instructions to: receive a data signal, wherein the received data signal is an aggregation of data signals received from one or more of the plurality of monitoring nodes, wherein the data signal includes at least one real-time stream of data source signal values that represent a current operation of the cyber-physical system; determine, via a trained classifier, whether the received data signal is a normal signal or an abnormal signal, wherein the trained classifier is trained with the generated abnormal data and normal data; localize an origin of an anomaly when it is determined the received data signal is the abnormal signal; receive the determination and localization at a resilient estimator module; execute the resilient estimator module to generate a state estimation for the cyber-physical system. Numerous other aspects are provided.