- 专利标题： EXO-AZA SPIRO INHIBITORS OF MENIN-MLL INTERACTION
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申请号： US17734413申请日： 2022-05-02
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公开(公告)号： US20230039917A1公开(公告)日： 2023-02-09
- 发明人: Xuedong DAI , Olivier Alexis Georges QUEROLLE , Daniel Jason KROSKY , Wei CAI , Liqiang FU , Linglong KONG , Yingtao LIU , Zhao-Kui WAN , Barbara MORSCHHÄUSER GEB. HERKERT , Vineet PANDE , James Patrick EDWARDS , Aaron Nathaniel PATRICK , Patrick René ANGIBAUD , Virginie Sophie PONCELET
- 申请人： Janssen Pharmaceutica NV
- 申请人地址： BE Beerse
- 专利权人： Janssen Pharmaceutica NV
- 当前专利权人： Janssen Pharmaceutica NV
- 当前专利权人地址： BE Beerse
- 优先权： CNPCT/CN2017/117536 20171220,CNPCT/CN2018/091521 20180615
- 主分类号： C07D495/04
- IPC分类号： C07D495/04 ; A61P35/00 ; C07D519/00
摘要：
The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes.
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