- 专利标题： QUINAZOLINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS
-
申请号： US17784557申请日： 2020-12-10
-
公开(公告)号： US20230063121A1公开(公告)日： 2023-03-02
- 发明人: Gabriele AMARI , Elisabetta ARMANI , Mafalda PAGANO , Luca RAVEGLIA , Marta GIULIANI , Claudia BEATO
- 申请人： CHIESI FARMACEUTICI S.P.A.
- 申请人地址： IT Parma
- 专利权人： CHIESI FARMACEUTICI S.P.A.
- 当前专利权人： CHIESI FARMACEUTICI S.P.A.
- 当前专利权人地址： IT Parma
- 优先权： EP19215719.6 20191212
- 国际申请： PCT/EP2020/085460 WO 20201210
- 主分类号： C07D417/12
- IPC分类号： C07D417/12 ; C07D239/94 ; C07D413/14 ; C07D409/12 ; C07D413/12 ; C07D417/14
摘要：
The present invention relates to a compounds of general formula (I) inhibiting lysophosphatidic acid receptor 2 (LPA2), particularly the invention relates to compounds that are quinazoline derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
信息查询
