A test and measurement device has an input port configured to receive a signal from a device under test, the signal having a symbol rate, one or more analog-to-digital converters to convert the signal to waveform samples at a sampling rate, and one or more processors configured to execute code that, when aliasing is present in the waveform samples, causes the one or more processors to: up-sample the waveform samples to produce up-sampled samples; use the up-sampled samples to produce a real-time waveform; perform clock recovery on the real-time waveform to produce a recovered clock; and resample the waveform samples using the recovered clock to produce a non-aliased waveform. A method of acquiring a waveform in a test and measurement device includes receiving a signal from a device under test, the signal having a symbol rate, converting the signal to waveform samples at a sampling rate of the test and measurement device, when aliasing is present in the waveform samples, up-sampling the waveform samples to produce up-sampled samples, using the up-sampled samples to produce a real-time waveform, performing clock recovery on the real-time waveform to produce a recovered clock, and resampling the waveform samples using the recovered clock to produce a non-aliased waveform.