Invention Application
- Patent Title: LILRB3 ANTIBODY MOLECULES AND USES THEREOF
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Application No.: US17799240Application Date: 2021-02-12
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Publication No.: US20230070339A1Publication Date: 2023-03-09
- Inventor: Björn FRENDÉUS , All Roghanian , Mark GRAGG
- Applicant: University of Southampton , BIOINVENT INTERNATIONAL AB
- Applicant Address: GB Southampton Hampshire; SE Lund
- Assignee: University of Southampton,BIOINVENT INTERNATIONAL AB
- Current Assignee: University of Southampton,BIOINVENT INTERNATIONAL AB
- Current Assignee Address: GB Southampton Hampshire; SE Lund
- Priority: EP20156969.6 20200212
- International Application: PCT/EP2021/053516 WO 20210212
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P37/06

Abstract:
Described are anti-LILRB3 antibody molecules, such as agonistic anti-LILRB3 antibody molecules for use in treatment of graft rejection or autoimmunity via reprograming of human myeloid cells. Described are also specific anti-LILRB3 antibody molecules and use of such antibody molecules in medicine, for example in treatment of graft rejection, autoimmune disorders or inflammatory disorders.
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