- 专利标题： SUSTAINED RELEASE COWPEA MOSAIC VIRUS OR VIRUS-LIKE PARTICLE THERAPEUTIC CONSTRUCTS FOR THE TREATMENT OF CANCER
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申请号： US17903286申请日： 2022-09-06
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公开(公告)号： US20230076403A1公开(公告)日： 2023-03-09
- 发明人: Nicole F. Steinmetz , Frank Alexander Veliz , Brylee David B. Tiu
- 申请人： CASE WESTERN RESERVE UNIVERSITY
- 申请人地址： US OH Cleveland
- 专利权人： CASE WESTERN RESERVE UNIVERSITY
- 当前专利权人： CASE WESTERN RESERVE UNIVERSITY
- 当前专利权人地址： US OH Cleveland
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K47/69 ; A61P35/00 ; A61K39/385 ; A61K39/39
摘要：
A nanoparticle construct includes a plurality of plant virus or virus-like particles electrostatically coupled to a plurality of nanoparticles having a different surface charge than the plant virus or virus-like particles. The nanoparticle construct upon delivery to a subject can provide a sustained release of the plant virus or virus-like particles and/or nanoparticles to a cell or tissue of the subject.
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