-
公开(公告)号：US20230076403A1
公开(公告)日：2023-03-09
申请号：US17903286
申请日：2022-09-06
IPC分类号： A61K39/00 , A61K47/69 , A61P35/00 , A61K39/385 , A61K39/39
摘要： A nanoparticle construct includes a plurality of plant virus or virus-like particles electrostatically coupled to a plurality of nanoparticles having a different surface charge than the plant virus or virus-like particles. The nanoparticle construct upon delivery to a subject can provide a sustained release of the plant virus or virus-like particles and/or nanoparticles to a cell or tissue of the subject.
-
公开(公告)号：US20210275651A1
公开(公告)日：2021-09-09
申请号：US16319765
申请日：2017-07-21
IPC分类号： A61K39/00 , A61K39/385 , A61K39/39 , A61K47/69 , A61P35/00
摘要： A nanoparticle construct includes a plurality of plant virus or virus-like particles electrostatically coupled to a plurality of nanoparticles having a different surface charge than the plant virus or virus-like particles. The nanoparticle construct upon delivery to a subject can provide a sustained release of the plant virus or virus-like particles and/or nanoparticles to a cell or tissue of the subject.
-
公开(公告)号：US11433123B2
公开(公告)日：2022-09-06
申请号：US16319765
申请日：2017-07-21
摘要： A method of treating cancer in a subject in need thereof includes administering in situ to cancer cells of the subject a nanoparticle construct that includes a plurality of cowpea mosaic virus or virus-like particles electrostatically coupled to a plurality of G4 dendrimers having a different surface charge than the cowpea mosaic virus or virus-like particles. The nanoparticle construct upon delivery to a subject can provide a sustained release of the cowpea mosaic virus or virus-like particles and/or G4 dendrimers to a cell or tissue of the subject. The cancer selected from the group consisting of melanoma, breast cancer, colon cancer, lung cancer, and ovarian cancer.
-
-
搜索结果
3 条记录 (耗时 0.014 秒)
