- 专利标题： COATING AGENT FOR INDUCING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO BRAIN MICROVASCULAR ENDOTHELIUM-LIKE CELLS AND USE THEREOF
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申请号： US17798206申请日： 2021-02-09
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公开(公告)号： US20230084457A1公开(公告)日： 2023-03-16
- 发明人: Tamihide MATSUNAGA , Tadahiro HASHITA , Hiromasa AOKI , Misaki YAMASHITA
- 申请人： PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY
- 申请人地址： JP Nagoya-shi, Aichi
- 专利权人： PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY
- 当前专利权人： PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY
- 当前专利权人地址： JP Nagoya-shi, Aichi
- 优先权： JP2020-021031 20200210
- 国际申请： PCT/JP2021/004762 WO 20210209
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; C12N5/071
摘要：
Provided is a technology allowing for stable supply of brain microvascular endothelium-like cells. This coating agent for inducing differentiation of pluripotent stem cells into brain microvascular endothelium-like cells contains at least one component of a Laminin-221 fragment or an N-terminal Vitronectin.
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