- 专利标题： SMALL MOLECULES FOR TREATING AGE-RELATED RETINAL DISEASES
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申请号： US17799546申请日： 2021-04-19
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公开(公告)号： US20230089949A1公开(公告)日： 2023-03-23
- 发明人: Lori Birder , Edwin Kerry Jackson , Amanda Wolf-Johnston , José-Alain Sahel , Yuanyuan Chen
- 申请人： University of Pittsburgh - Of the Commonwealth System of Higher Education
- 申请人地址： US PA Pittsburgh
- 专利权人： University of Pittsburgh - Of the Commonwealth System of Higher Education
- 当前专利权人： University of Pittsburgh - Of the Commonwealth System of Higher Education
- 当前专利权人地址： US PA Pittsburgh
- 国际申请： PCT/US2021/027991 WO 20210419
- 主分类号： A61K31/522
- IPC分类号： A61K31/522 ; A61P27/02
摘要：
Disclosed herein are methods of treating age-related retinal diseases by administering to the subject a therapeutically effective amount of a purine nucleoside phosphorylase (PNPase) inhibitor and/or a PNPase purine nucleoside substrate. In some examples, the subject can have AMD or glaucoma.
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