Systems, apparatuses and methods may provide technology for optimizing an inference neural network model that performs asymmetric quantization by generating a quantized neural network, wherein model weights of the neural network are quantized as signed integer values, and wherein an input layer of the neural network is configured to quantize input values as unsigned integer values, generating a weights accumulation table based on the quantized model weights and a kernel size for the neural network, and generating an output restoration function for an output layer of the neural network based on the weights accumulation table and the kernel size. The technology may also perform per-input channel quantization. The technology may also perform mixed-precision auto-tuning.