COMPOSITIONS AND METHODS FOR DIAGNOSING AND ASSESSING RHEUMATOID ARTHRITIS USING PROTEIN-ARGININE DEIMINASE 1 (PAD1) AUTOANTIGENS
摘要:
The present disclosure relates to the use of PAD proteins, such as PAD1, or PAD1 and PAD4, or antigenic fragments thereof as clinical biomarker for diagnostic and prognostic information in rheumatoid arthritis (RA) patients. The disclosure further provides methods and compositions for the detection of autoantibodies against PAD proteins, such as anti-PAD1, or anti-PAD1 and anti-PAD4, in a biological sample.
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