- 专利标题: COMPOSITIONS AND METHODS FOR DIAGNOSING AND ASSESSING RHEUMATOID ARTHRITIS USING PROTEIN-ARGININE DEIMINASE 1 (PAD1) AUTOANTIGENS
-
申请号: US17961412申请日: 2022-10-06
-
公开(公告)号: US20230118822A1公开(公告)日: 2023-04-20
- 发明人: Michael MAHLER , Laura MARTINEZ-PRAT , Chelsea BENTOW
- 申请人: INOVA DIAGNOSTICS, INC.
- 申请人地址: US CA SAN DIEGO
- 专利权人: INOVA DIAGNOSTICS, INC.
- 当前专利权人: INOVA DIAGNOSTICS, INC.
- 当前专利权人地址: US CA SAN DIEGO
- 主分类号: G01N33/564
- IPC分类号: G01N33/564
摘要:
The present disclosure relates to the use of PAD proteins, such as PAD1, or PAD1 and PAD4, or antigenic fragments thereof as clinical biomarker for diagnostic and prognostic information in rheumatoid arthritis (RA) patients. The disclosure further provides methods and compositions for the detection of autoantibodies against PAD proteins, such as anti-PAD1, or anti-PAD1 and anti-PAD4, in a biological sample.
信息查询
IPC分类: