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公开(公告)号:US20160091490A1
公开(公告)日:2016-03-31
申请号:US14806515
申请日:2015-07-22
发明人: Michael MAHLER , Leendert A. TROUW
IPC分类号: G01N33/564 , C07K1/107 , C07K14/81
CPC分类号: G01N33/564 , C07K1/1075 , C07K14/8125 , G01N2333/8125 , G01N2440/00 , G01N2800/102
摘要: The present disclosure relates to the field of molecular biology and more specifically to methods for detecting anti-carbamylated protein (anti-CarP) antibodies in the serum of rheumatoid arthritis (RA) patients.
摘要翻译: 本公开涉及分子生物学领域,更具体地涉及用于在类风湿性关节炎(RA)患者血清中检测抗氨基甲酰化蛋白质(抗CarP)抗体的方法。
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公开(公告)号:US20170199187A1
公开(公告)日:2017-07-13
申请号:US15321491
申请日:2015-06-23
发明人: Michael MAHLER
IPC分类号: G01N33/564
CPC分类号: G01N33/564 , C07K2319/40 , C12N9/22 , C12Y301/26005 , G01N2800/101
摘要: The present disclosure relates to the field of molecular biology and immunology. More specifically, the present disclosure provides compositions and methods for detecting anti-Th/To autoantibodies in the serum of subject with a systemic autoimmune disease, such as systemic sclerosis (SSc).
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公开(公告)号:US20230118822A1
公开(公告)日:2023-04-20
申请号:US17961412
申请日:2022-10-06
IPC分类号: G01N33/564
摘要: The present disclosure relates to the use of PAD proteins, such as PAD1, or PAD1 and PAD4, or antigenic fragments thereof as clinical biomarker for diagnostic and prognostic information in rheumatoid arthritis (RA) patients. The disclosure further provides methods and compositions for the detection of autoantibodies against PAD proteins, such as anti-PAD1, or anti-PAD1 and anti-PAD4, in a biological sample.
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公开(公告)号:US20180038856A1
公开(公告)日:2018-02-08
申请号:US15791354
申请日:2017-10-23
发明人: Michael MAHLER , Leendert A. TROUW , Jan Wouter DRIJFHOUT , Tom HUIZINGA , René TOES , Peter VAN VEELEN
IPC分类号: G01N33/564 , C07K1/107 , C07K14/81
摘要: The present disclosure relates to the field of molecular biology and more specifically to methods for detecting anti-carbamylated protein (anti-CarP) antibodies in the serum of rheumatoid arthritis (RA) patients.
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