Invention Application
- Patent Title: Development of a Simple, Low-Cost Method of Measuring Ammonia Concentration in Exhaled Breath for Routine Monitoring of Chronic Kidney Disease
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Application No.: US17517919Application Date: 2021-11-03
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Publication No.: US20230133069A1Publication Date: 2023-05-04
- Inventor: Riley Rapert , Robert A. Latour , George Chumanov , Tyler George Harvey , Guzeliya Korneva
- Applicant: Clemson University Research Foundation
- Applicant Address: US SC Clemson
- Assignee: Clemson University Research Foundation
- Current Assignee: Clemson University Research Foundation
- Current Assignee Address: US SC Clemson
- Main IPC: A61B5/08
- IPC: A61B5/08 ; A61B5/097

Abstract:
Provided is an apparatus for measuring the ammonia concentration in exhaled breath and a method for measuring the ammonia concentration in exhaled breath. The apparatus comprises a sample collection portion, capable of capturing exhaled breath to control the volume of exhaled breath, a pressure gauge for the control of the flow rate of exhaled breath, a small diameter inner tube oriented in a perpendicular direction to the colorimetric sensor to focus the exhaled breath stream onto the central region of the sensor, and an analysis portion capable of receiving said exhaled breath from said sample collection portion. The analysis portion comprises a colorimetric sensor comprising an active component on a substrate. The colorimetric sensor changes color proportional to the ammonia concentration in said exhaled breath.
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