- 专利标题: RIPK2 INHIBITION FOR THE TREATMENT OF CANCER
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申请号: US17913760申请日: 2021-03-29
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公开(公告)号: US20230139516A1公开(公告)日: 2023-05-04
- 发明人: Wei Yang
- 申请人: CEDARS-SINAI MEDICAL CENTER
- 申请人地址: US CA Los Angeles
- 专利权人: CEDARS-SINAI MEDICAL CENTER
- 当前专利权人: CEDARS-SINAI MEDICAL CENTER
- 当前专利权人地址: US CA Los Angeles
- 国际申请: PCT/US2021/024740 WO 20210329
- 主分类号: A61K31/5025
- IPC分类号: A61K31/5025 ; A61P35/02 ; C12Q1/6886
摘要:
Described herein are treatments and patient selection methods for cancers such as prostate cancer, breast cancer, liver cancer, bladder cancer, and melanoma. The treatment involves administering a RIPK2 inhibitor to a subject. The patient selection involves selecting a patient who has increased copy numbers or expression of both RIPK2 and MYC.