- 专利标题： COMPOSITIONS AND METHODS OF INHIBITING THE BINDING OF PLASMA IGG AUTOANTIBODIES TO SEROTONIN 2A RECEPTOR
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申请号： US18038588申请日： 2021-11-22
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公开(公告)号： US20240002467A1公开(公告)日： 2024-01-04
- 发明人: Mark B. Zimering
- 申请人： UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- 申请人地址： US DC Washington
- 专利权人： UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- 当前专利权人： UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- 当前专利权人地址： US DC Washington
- 国际申请： PCT/US2021/060306 2021.11.22
- 进入国家日期： 2023-05-24
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; A61K47/54 ; G01N33/564 ; A61P3/06 ; A61P3/04 ; A61P9/12 ; A61K31/506 ; A61K31/445
摘要：
Disclosed herein, are decoy peptides or polypeptides capable of inhibiting binding of 5-HT2A autoantibodies to a second extracellular loop region of the 5-HT2A receptor, and a pharmaceutical composition containing the decoy peptides or polypeptides and methods of use.
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