A compression garment for circulatory-related disorder therapy includes a skin contacting layer, a second layer coupled to the skin contacting layer, and connectors disposed on the second layer. The skin contacting layer and the second layer form one or more macro-chambers. Each macro-chamber is partitioned into a plurality of micro-chambers. Each of the micro-chambers is in direct fluid communication with at least one other of the micro-chambers. Each of the connectors is configured to supply pressurized air directly into at least a corresponding one of the macro-chambers such that the pressurized air is delivered to at least one of the micro-chambers within the macro-chamber. The coupling of the skin contacting layer and the second layer is along a layer attachment profile that defines the macro-chambers and the micro-chambers. At least one of the micro-chambers is linked to another of the micro-chambers by way of a plurality of openings.