发明公开
- 专利标题： MEDIATORS OF GENE SILENCING
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申请号： US18254324申请日： 2021-11-24
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公开(公告)号： US20240011037A1公开(公告)日： 2024-01-11
- 发明人: Monika Gullerova
- 申请人： CANCER RESEARCH TECHNOLOGY LIMITED
- 申请人地址： GB Greater London
- 专利权人： CANCER RESEARCH TECHNOLOGY LIMITED
- 当前专利权人： CANCER RESEARCH TECHNOLOGY LIMITED
- 当前专利权人地址： GB Greater London
- 优先权： GB 18570.8 2020.11.25
- 国际申请： PCT/GB2021/053039 2021.11.24
- 进入国家日期： 2023-05-24
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; C12N9/22 ; A61P35/00
摘要：
The present invention relates to a method of inhibiting expression of a gene in a biological system. The method of the present invention comprises introducing a tRNA-derived polynucleotide into the biological system. The tRNA-derived polynucleotide of 5 the present invention comprises a sequence that is complementary to an intronic region or exonic region of the gene whose expression is to be inhibited.
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