- 专利标题： AMIDATED PEPTIDES AND THEIR DEAMIDATED COUNTERPARTS DISPLAYED BY HLA-A*02 FOR USE IN IMMUNOTHERAPY AGAINST DIFFERENT TYPES OF CANCERS
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申请号： US18451883申请日： 2023-08-18
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公开(公告)号： US20240016909A1公开(公告)日： 2024-01-18
- 发明人: Jens HUKELMANN , Heiko SCHUSTER , Ricarda HANNEN , Christoph SCHRAEDER , Jens FRITSCHE , Franziska HOFFGAARD , Daniel Johannes KOWALEWSKI , Oliver SCHOOR
- 申请人： Immatics Biotechnologies GmbH
- 申请人地址： DE Tuebingen
- 专利权人： Immatics Biotechnologies GmbH
- 当前专利权人： Immatics Biotechnologies GmbH
- 当前专利权人地址： DE Tuebingen
- 分案原申请号： US17489557 2021.09.29
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61P35/00 ; C07K14/705 ; C07K14/74
摘要：
The invention relates to a peptide comprising an amino acid sequence selected from the group consisting of (i) SEQ ID NO: 1 to SEQ ID NO: 102, and (ii) a variant sequence thereof which maintains capacity to bind to MHC molecule(s) and/or induce T cells cross-reacting with said variant peptide, or a pharmaceutically acceptable salt thereof.
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