A method for deblurring a blurred image includes dividing the blurred image into overlapping regions each having a size and an offset from neighboring overlapping regions along a first direction as determined by a period of a ringing artifact in the blurred image, or by obtained blur characteristics relating to the blurred image and/or attributable to the optical system, or by a detected cause capable of producing the blur characteristics, stacking the overlapping regions to produce a stacked output, wherein the overlapping regions are sequentially organized along the first direction, convolving the stacked output through a first convolutional neural network (CNN) to produce a first CNN output having reduced blur as compared to the stacked output, and assembling the first CNN output into a re-assembled image, and processing the re-assembled image through a second CNN to produce a deblurred image having reduced residual artifacts as compared to the re-assembled image.