Systems and methods may provide assessment tools such as assessment prompts, to solicit feedback from patients at regular intervals, track patient progress, and recommend VR activities. A VR therapy platform may use a VR assessment to request patient feedback related to conditions such as anxiety, depression, and/or pain. Based on patient-provided assessment responses, a VR therapy platform may categorize the patient responses and recommend one or more appropriate VR activities to help reduce the intensity of the patient's reported state(s). In some embodiments, VR activity recommendations may be based on patient-reported feedback and biometric measurements. In some embodiments, a VR therapy platform may compare a patient's assessment responses with biometric measurements taken at or around the same time, along with a patient's health history, to determine whether patient responses may be contradictory or biased, and thus potentially requiring adjustment prior to recommending VR activities.