Provided by the present disclosure are an image acquisition device, an image acquisition apparatus, an image acquisition method and a manufacturing method. The image acquisition device includes: image sensing member groups each including a plurality of image sensing members, and each image sensing member includes a photosensitive assembly with photosensitive components, and a lens assembly covering a photosensitive side of the photosensitive assembly; and shielding portions corresponding to the photosensitive components in a one-to-one correspondence. Each image sensing member group corresponds to a photography depth, and the plurality of image sensing member groups correspond to a plurality of photography depths. For the plurality of image sensing member groups at least one of following is included: the arrangement modes of the image sensing members in the image sensing member groups are different, and camera intrinsic parameters of the image sensing members in the image sensing member groups are different.