- 专利标题： SHORT-ACTING HEPARIN-BASED ANTICOAGULANT COMPOUNDS AND METHODS
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申请号： US18222910申请日： 2023-07-17
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公开(公告)号： US20240066048A1公开(公告)日： 2024-02-29
- 发明人: Jian Liu , Zhangjie Wang , Po-Hung Hsieh , Yongmei Xu
- 申请人： The University of North Carolina at Chapel Hill
- 申请人地址： US NC Chapel Hill
- 专利权人： The University of North Carolina at Chapel Hill
- 当前专利权人： The University of North Carolina at Chapel Hill
- 当前专利权人地址： US NC Chapel Hill
- 分案原申请号： US16492858 2019.09.10
- 主分类号： A61K31/727
- IPC分类号： A61K31/727 ; A61K38/48 ; A61P7/02 ; C08B37/00 ; C12P19/04 ; C12P19/18
摘要：
Heparin compounds and synthetic heparin analogues having short acting anticoagulant activity are provided. Methods of synthesizing such heparin compounds, including chemoenzymatic pathways using sulfotransferase enzymes are provided. Methods of treating subjects in need of anticoagulant activity are provided.
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