- 专利标题： EXPEC GLYCOCONJUGATE VACCINE FORMULATIONS
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申请号： US18503294申请日： 2023-11-07
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公开(公告)号： US20240082412A1公开(公告)日： 2024-03-14
- 发明人: Olga LABOVITIADI , Wouter Frank TONNIS , Francesco DORO , Janik ADRIAANSEN
- 申请人： Janssen Pharmaceuticals, Inc.
- 申请人地址： US NJ Titusville
- 专利权人： Janssen Pharmaceuticals, Inc.
- 当前专利权人： Janssen Pharmaceuticals, Inc.
- 当前专利权人地址： US NJ Titusville
- 优先权： EP 195256.9 2016.10.24
- 主分类号： A61K47/64
- IPC分类号： A61K47/64 ; A61K39/108 ; A61K47/02 ; A61K47/20 ; A61K47/26 ; A61K47/65 ; C08B37/00
摘要：
Compositions and methods for inducing an immune response against extra-intestinal pathogenic Escherichia coli (ExPEC) are described. In particular, multivalent vaccines containing O-antigen polysaccharide covalently bound to an exotoxin A of Pseudomonas aeruginosa (EPA) carrier protein that can withstand multiple environmental stresses are describe.
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