Provided is a method of creating a QoS flow for a time synchronization protocol in a wireless communication network. A method of creating a QoS flow for a time synchronization protocol in a wireless communication network includes: receiving, by a Session Management Function (SMF), the PTP profile information from the UE, together with at least one of a DNN, a S-NSSAI information and a session ID for a Time Sensitive Communication (TSC) service; setting, by the SMF, a PCCrule of the QoS flow for the time synchronization protocol; providing, by the SMF, the QoS flow and a SDF filter information for the QoS flow to a User Plane Function (UPF); and providing, by the SMF, the QoS flow and a QoS rule filter to an Access and Mobility Management Function (AMF).