- 专利标题： NEUTRALIZING ANTIBODIES TO PLASMODIUM FALCIPARUM CIRCUMSPOROZOITE PROTEIN AND THEIR USE
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申请号： US18364104申请日： 2023-08-02
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公开(公告)号： US20240117026A1公开(公告)日： 2024-04-11
- 发明人: Robert Seder , Neville Kisalu , Azza Idris , Barbara Flynn , Stephen Hoffman
- 申请人： The U.S.A., as Represented by the Secretary, Department of Health and Human Services , Sanaria Inc.
- 申请人地址： US MD Bethesda
- 专利权人： The U.S.A., as Represented by the Secretary, Department of Health and Human Services,Sanaria Inc.
- 当前专利权人： The U.S.A., as Represented by the Secretary, Department of Health and Human Services,Sanaria Inc.
- 当前专利权人地址： US MD Bethesda; US MD Rockville
- 主分类号： C07K16/20
- IPC分类号： C07K16/20
摘要：
Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.
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