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公开(公告)号:US20240117026A1
公开(公告)日:2024-04-11
申请号:US18364104
申请日:2023-08-02
申请人: The U.S.A., as Represented by the Secretary, Department of Health and Human Services , Sanaria Inc.
发明人: Robert Seder , Neville Kisalu , Azza Idris , Barbara Flynn , Stephen Hoffman
IPC分类号: C07K16/20
CPC分类号: C07K16/205 , C07K2317/21 , C07K2317/34 , C07K2317/76 , C07K2317/92
摘要: Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.
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公开(公告)号:US11021535B2
公开(公告)日:2021-06-01
申请号:US16485354
申请日:2018-02-12
申请人: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES , SANARIA INC
发明人: Robert Seder , Neville Kisalu , Azza Idris , Barbara Flynn , Stephen Hoffman
IPC分类号: C07K16/20
摘要: Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.
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公开(公告)号:US11760794B2
公开(公告)日:2023-09-19
申请号:US17243455
申请日:2021-04-28
申请人: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES , Sanaria Inc.
发明人: Robert Seder , Neville Kisalu , Azza Idris , Barbara Flynn , Stephen Hoffman
IPC分类号: C07K16/20
CPC分类号: C07K16/205 , C07K2317/21 , C07K2317/34 , C07K2317/76 , C07K2317/92
摘要: Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.
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公开(公告)号:US20210253683A1
公开(公告)日:2021-08-19
申请号:US17243455
申请日:2021-04-28
申请人: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC , Sanaria Inc.
发明人: Robert Seder , Neville Kisalu , Azza Idris , Barbara Flynn , Stephen Hoffman
IPC分类号: C07K16/20
摘要: Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.
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