- 专利标题: VL ANTIGEN BINDING PROTEINS EXHIBITING DISTINCT BINDING CHARACTERISTICS
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申请号: US18538999申请日: 2023-12-13
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公开(公告)号: US20240124613A1公开(公告)日: 2024-04-18
- 发明人: Robert Babb , Ashique Rafique , Tammy T. Huang , Ergang Shi , Lynn Macdonald , Andrew J. Murphy
- 申请人: Regeneron Pharmaceuticals, Inc.
- 申请人地址: US NY Tarrytown
- 专利权人: Regeneron Pharmaceuticals, Inc.
- 当前专利权人: Regeneron Pharmaceuticals, Inc.
- 当前专利权人地址: US NY Tarrytown
- 分案原申请号: US16996302 2020.08.18
- 主分类号: C07K16/44
- IPC分类号: C07K16/44 ; A01K67/027 ; C07K16/00 ; C12N15/85 ; G01N33/68
摘要:
Methods for making, identifying, isolating and/or making binding proteins that contain an immunoglobulin light chain variable domain, including a somatically hypermutated light chain variable domain, fused with a heavy chain constant region, are provided. Exemplary binding proteins specific to small molecules are also provided.
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