Invention Publication
- Patent Title: ANTIBODY-DRUG CONJUGATE
-
Application No.: US18237663Application Date: 2023-08-24
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Publication No.: US20240148895A1Publication Date: 2024-05-09
- Inventor: Masayuki MIYANO , Yuya NAKAZAWA , Kentaro ISO , Yuki YABE , Hirotatsu UMIHARA , Junichi TAGUCHI , Satoshi INOUE , Shuntaro TSUKAMOTO , Hiroyuki KOGAI , Atsumi YAMAGUCHI , Tsuyoshi AKAGI , Yohei MUKAI , Toshifumi HIRAYAMA , Masaki KATO , Toshiki MOCHIZUKI , Akihiko YAMAMOTO , Yuji YAMAMOTO , Takato SAKURADA
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Main IPC: A61K47/68
- IPC: A61K47/68

Abstract:
An antibody-drug conjugate represented by formula (I):
(where
Ab is an antibody,
X is a group represented by formula (X-1), formula (X-2) or formula (X-3):
(where
at the left represents the binding site with NH and
at the right represents the binding side with D),
D is a group represented by formula (D-1) or formula (D-2):
(where
represents the binding site with X), and
n is in the range of about 1 to about 8).
(where
Ab is an antibody,
X is a group represented by formula (X-1), formula (X-2) or formula (X-3):
(where
at the left represents the binding site with NH and
at the right represents the binding side with D),
D is a group represented by formula (D-1) or formula (D-2):
(where
represents the binding site with X), and
n is in the range of about 1 to about 8).
Information query
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