Invention Publication
- Patent Title: PYRIDIN-2(1H)-ONE QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS
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Application No.: US18506060Application Date: 2023-11-09
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Publication No.: US20240150319A1Publication Date: 2024-05-09
- Inventor: Jian Lin , Anna Ericsson , Ann-Marie Campbell , Gary Gustafson , Zhongguo Wang , R. Bruce Diebold , Susan Ashwell , David R. Lancia, JR. , Justin Andrew Caravella , Wei Lu
- Applicant: FORMA Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: FORMA Therapeutics, Inc.
- Current Assignee: FORMA Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61P35/00 ; C07D401/14 ; C07D471/04
Abstract:
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula:
where A, U, W1, W2, W3, R1-R6, and R9 are described herein.
where A, U, W1, W2, W3, R1-R6, and R9 are described herein.
Information query
