Invention Publication
- Patent Title: NITROGEN-CONTAINING SPIRO CYCLIC COMPOUNDS AND PHARMACEUTICAL USE THEREOF
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Application No.: US18143720Application Date: 2023-05-05
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Publication No.: US20240150367A1Publication Date: 2024-05-09
- Inventor: Satoru Noji , Makoto Shiozaki , Tomoya Miura , Yoshinori Hara , Hiroshi Yamanaka , Katsuya Maeda , Akimi Hori , Masafumi Inoue , Yasunori Hase
- Applicant: Japan Tobacco Inc.
- Applicant Address: JP Tokyo
- Assignee: Japan Tobacco Inc.
- Current Assignee: Japan Tobacco Inc.
- Current Assignee Address: JP Tokyo
- Priority: JP 09179502 2009.07.31
- Main IPC: C07D487/10
- IPC: C07D487/10 ; A61K31/437 ; A61K31/438 ; A61K31/519 ; A61K31/55 ; C07D471/10 ; C07D519/00

Abstract:
A compound of the following general formula [I]:
wherein each symbol has the same meaning as defined herein, or a pharmaceutically acceptable salt thereof, or a solvate thereof, and a pharmaceutical use of the same in treating organ transplant rejection, graft versus host reaction after transplantation, autoimmune disease, allergic disease and chronic myeloproliferative disease.
wherein each symbol has the same meaning as defined herein, or a pharmaceutically acceptable salt thereof, or a solvate thereof, and a pharmaceutical use of the same in treating organ transplant rejection, graft versus host reaction after transplantation, autoimmune disease, allergic disease and chronic myeloproliferative disease.
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