Invention Publication
- Patent Title: COMPOSITION FOR DIFFERENTIAL DIAGNOSIS OF MALIGNANT PERIPHERAL NERVE SHEATH TUMOR
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Application No.: US18552133Application Date: 2022-03-21
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Publication No.: US20240175872A1Publication Date: 2024-05-30
- Inventor: Chong Jai KIM , Kyung Gon KIM , Beom Hee LEE , Eun Na KIM , Min Hoo CHANG , Hwangkyo JEONG , Hyo-Sang DO
- Applicant: THE ASAN FOUNDATION , UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION , HUMANSCAPE INC.
- Applicant Address: KR Seoul
- Assignee: THE ASAN FOUNDATION,UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION,HUMANSCAPE INC.
- Current Assignee: THE ASAN FOUNDATION,UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION,HUMANSCAPE INC.
- Current Assignee Address: KR Seoul; KR Ulsan; KR Seoul
- Priority: KR 20210037912 2021.03.24 KR 20220034295 2022.03.18
- International Application: PCT/KR2022/003918 2022.03.21
- Date entered country: 2023-09-22
- Main IPC: G01N33/574
- IPC: G01N33/574 ; C12Q1/6886 ; G01N33/50

Abstract:
The present invention relates to a composition for the differential diagnosis of malignant peripheral nerve sheath tumor (MPNST), a differential diagnosis kit comprising same, a method for providing information required for differential diagnosis of MPNST using same, a method for screening materials for preventing, alleviating, and treating MPNST, and the like. Using the composition capable of detecting the protein marker of the present invention has the effect of making it possible to predict and diagnose whether a malignant tumor has occurred in a patient with neurofibromatosis type 1.
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